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To end the AIDS epidemic by 2030, the global response to HIV must leave no one behind, including people who inject drugs. It requires drug policies and HIV-related prevention, treatment, care and support services that meet both the human rights and the health needs of people who inject drugs. Estimates show that worldwide there are approximately 12 million people who inject drugs, 1.6 million (14%) of whom are living with HIV and 6 million (50%) of whom are living with hepatitis C. HIV prevalence among women who inject drugs is often greater than among their male peers. UNAIDS estimates that 140 000 people who inject drugs were newly infected with HIV globally in 2014 and there has been no decline in the annual number of new HIV infections among people who inject drugs between 2010 and 2014.