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Public Safety Canada This research report provides evaluation results for the Life Skill Training (LST) program implemented in Edmonton, Alberta. LST is a prevention program targeting adolescent drug and alcohol use. Implementing and evaluating model programs provides an opportunity to assess what factors contribute to changes amongst different target populations in a variety of contexts. This evaluation research study was conducted between 2010 and 2014 and was adapted to an Aboriginal population. Valid conclusions regarding the effect of the LST program on substance use onset was unable to be drawn from the data available, as the project experienced challenges with enrolment, participant retention and drop-outs. Qualitative findings on most variables, however, were positive.